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Source language
Original Greek   
θύρα γάρ μοι ἀνέῳγεν μεγάλη καὶ ἐνεργής, καὶ ἀντικείμενοι πολλοί.
Greek - Transliteration via code library   
thura gar moi aneogen megale kai energes, kai antikeimenoi polloi.

Intermediate language
Vulgate (Latin)   
ostium enim mihi apertum est magnum et evidens et adversarii multi

King James Variants
American King James Version   
For a great door and effectual is opened to me, and there are many adversaries.
King James 2000 (out of print)   
For a great and effective door is opened unto me, and there are many adversaries.
King James Bible (Cambridge, large print)   
For a great door and effectual is opened unto me, and there are many adversaries.

Other translations
American Standard Version   
for a great door and effectual is opened unto me, and there are many adversaries.
Aramaic Bible in Plain English   
For a great door is opened to me, filled with opportunities and many opponents.
Darby Bible Translation   
For a great door is opened to me and an effectual one, and the adversaries many.
Holy Bible: Douay-Rheims Version (Genuine Leather Black)   
For a great door and evident is opened unto me: and many adversaries.
ERV 1885 English Revised Version with Strong's Concordance   
for a great door and effectual is opened unto me, and there are many adversaries.
English Standard Version Journaling Bible   
for a wide door for effective work has opened to me, and there are many adversaries.
God's Word   
I have a great opportunity to do effective work here, although there are many people who oppose me.
Holman Christian Standard Bible   
because a wide door for effective ministry has opened for me--yet many oppose me.
International Standard Version   
because a door has opened wide for me to do effective work, although many people are opposing me.
NET Bible   
because a door of great opportunity stands wide open for me, but there are many opponents.
New American Standard Bible   
for a wide door for effective service has opened to me, and there are many adversaries.
New International Version   
because a great door for effective work has opened to me, and there are many who oppose me.
New Living Translation   
There is a wide-open door for a great work here, although many oppose me.
Webster's Bible Translation   
For a great door and effectual is opened to me, and there are many adversaries.
Weymouth New Testament   
for a wide door stands open before me which demands great efforts, and we have many opponents.
The World English Bible   
for a great and effective door has opened to me, and there are many adversaries.